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Target
Neurotensin receptor type 1
Ligand
BDBM50281813
Substrate
n/a
Meas. Tech.
ChEBML_144305
Ki
3857±n/a nM
Citation
 Christos, TE; Arvanitis, A; Cain, GA; Johnson, AL; Pottorf, RS; Tam, S; Schmidt, WK Stable isosteres of neurotensin c-terminal pentapeptides derived by modification of the amide function Bioorg Med Chem Lett 3:1035-1040 (1993)    Article 
Target
Name:
Neurotensin receptor type 1
Synonyms:
NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1
Type:
PROTEIN
Mol. Mass.:
47070.64
Organism:
Rattus norvegicus
Description:
ChEMBL_1466612
Residue:
424
Sequence:
MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
  
Inhibitor
Name:
BDBM50281813
Synonyms:
(S)-2-((2S,3S)-2-{N'-[(S)-3-[((S)-1-{(S)-3-[(Adamantane-1-carbonyl)-amino]-7-amino-2-oxo-heptylamino}-pyrrolidine-2-carbonyl)-amino]-4-(4-hydroxy-phenyl)-2-oxo-butyl]-hydrazino}-3-methyl-pentanoylamino)-4-methyl-pentanoic acid | CHEMBL429903
Type:
Small organic molecule
Emp. Form.:
C45H72N8O8
Mol. Mass.:
853.102
SMILES:
CC[C@H](C)[C@H](NNCC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1NCC(=O)[C@H](CCCCN)NC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2)C(=O)N[C@@H](CC(C)C)C(O)=O |TLB:47:42:49:48.46.45,47:46:49:41.42.43|
Structure:
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