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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50281863
Substrate
n/a
Meas. Tech.
ChEBML_99986
IC50
0.600000±n/a nM
Citation
 Guay, D; Gauthier, JY; Metters, KM; Roy, P; Zamboni, RJ A new series of potent LTD4 antagonists in the styrylquinoline class. Bioorg Med Chem Lett 3:1125-1130 (1993)    Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50281863
Synonyms:
CHEMBL14451 | Sodium; (S)-6-{3-[2-(7-chloro-quinolin-2-yl)-ethyl]-phenyl}-6-[2-(1-hydroxy-1-methyl-ethyl)-benzylsulfanyl]-3,3-dimethyl-hexanoate
Type:
Small organic molecule
Emp. Form.:
C35H39ClNO3S
Mol. Mass.:
589.208
SMILES:
CC(C)(CC[C@H](SCc1ccccc1C(C)(C)O)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1)CC([O-])=O
Structure:
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