Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50281915
Substrate
n/a
Meas. Tech.
ChEBML_209595
Kd
3.3±n/a nM
Citation
 Das, J; Hall, SE; Reid, JA; Han, WC; Harris, DN; Goldenberg, H; Michel, IM; Monshizadegan, H; Webb, ML Syntheses of Cyclopentane, Cyclohexene and Olefin Oxazoles as Thromboxane A2/Endoperoxide Receptor Antagonists Bioorg Med Chem Lett 3:1267-1270 (1993)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50281915
Synonyms:
3-(2-{2-[4-(4-Chloro-benzylcarbamoyl)-oxazol-2-yl]-cyclopentylmethyl}-phenyl)-propionic acid | CHEMBL23711
Type:
Small organic molecule
Emp. Form.:
C26H27ClN2O4
Mol. Mass.:
466.957
SMILES:
OC(=O)CCc1ccccc1C[C@H]1CCC[C@@H]1c1nc(co1)C(=O)NCc1ccc(Cl)cc1
Structure:
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