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Target
Thromboxane A2 receptor
Ligand
BDBM50282142
Substrate
n/a
Meas. Tech.
ChEMBL_210119 (CHEMBL814435)
IC50
>100000±n/a nM
Citation
 Yokota, M; Imamaki, K; Uchibori, S; Kondo, M; Kosakai, K; Tomiyama, T Role of sulfonamide moiety in non-prostanoid txa2 receptor antagonist kt2-962 : modifications of this moiety and the resulting activities Bioorg Med Chem Lett 3:1687-1692 (1993)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36943.05
Organism:
RAT
Description:
Thromboxane A2 TBXA2R RAT::P34978
Residue:
341
Sequence:
MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
  
Inhibitor
Name:
BDBM50282142
Synonyms:
3-[(2-Benzoylamino-acetylamino)-methyl]-6-isopropyl-azulene-1-carboxylic acid | CHEMBL297439
Type:
Small organic molecule
Emp. Form.:
C24H24N2O4
Mol. Mass.:
404.4584
SMILES:
CC(C)c1ccc2c(CNC(=O)CNC(=O)c3ccccc3)cc(C(O)=O)c2cc1
Structure:
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