Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50282146
Substrate
n/a
Meas. Tech.
ChEBML_210120
IC50
1500±n/a nM
Citation
 Yokota, M; Imamaki, K; Uchibori, S; Kondo, M; Kosakai, K; Tomiyama, T Role of sulfonamide moiety in non-prostanoid txa2 receptor antagonist kt2-962 : modifications of this moiety and the resulting activities Bioorg Med Chem Lett 3:1687-1692 (1993)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36943.05
Organism:
RAT
Description:
Thromboxane A2 TBXA2R RAT::P34978
Residue:
341
Sequence:
MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
  
Inhibitor
Name:
BDBM50282146
Synonyms:
CHEMBL48013 | Sodium; 6-isopropyl-3-(4-phenylsulfamoyl-butyl)-azulene-1-sulfonate
Type:
Small organic molecule
Emp. Form.:
C23H26NO5S2
Mol. Mass.:
460.587
SMILES:
CC(C)c1ccc2c(CCCCS(=O)(=O)Nc3ccccc3)cc(c2cc1)S([O-])(=O)=O
Structure:
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