Reaction Details Report a problem with these data
Target
Beta-lactamase TEM
Ligand
BDBM50282571
Substrate
n/a
Meas. Tech.
ChEBML_164508
Ki
83000±n/a nM
Citation
 Martin, R; Gold, M; Jones, J Inhibition of the RTEM-1 β-lactamase by boronic acids Bioorg Med Chem Lett 4:1229-1234 (1994)    Article 
Target
Name:
Beta-lactamase TEM
Synonyms:
BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla
Type:
Enzyme
Mol. Mass.:
31512.33
Organism:
Escherichia coli
Description:
P62593
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM50282571
Synonyms:
3-Bromophenyl boronic acid | CHEMBL278140
Type:
Small organic molecule
Emp. Form.:
C6H6BBrO2
Mol. Mass.:
200.826
SMILES:
OB(O)c1cccc(Br)c1
Structure:
Search PDB for entries with ligand similarity: