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Target
Peptidyl-prolyl cis-trans isomerase FKBP4
Ligand
BDBM50283391
Substrate
n/a
Meas. Tech.
ChEBML_154484
Ki
90000±n/a nM
Citation
 Luengo, JI; Konialian-Beck, A; Levy, MA; Brandt, M; Eggleston, DS; Holt, DA Synthesis and structure-activity relationships of macrocyclic FKBP ligands Bioorg Med Chem Lett 4:321-324 (1994)    Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP4
Synonyms:
FK506 binding protein 4 | FKBP4 | FKBP4_HUMAN | FKBP52
Type:
PROTEIN
Mol. Mass.:
51793.87
Organism:
Homo sapiens (Human)
Description:
ChEMBL_154482
Residue:
459
Sequence:
MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
  
Inhibitor
Name:
BDBM50283391
Synonyms:
7,7-Dimethyl-tetradecahydro-9,20-dioxa-4a-aza-benzocyclononadecene-5,6,10,21-tetraone | CHEMBL320252
Type:
Small organic molecule
Emp. Form.:
C22H35NO6
Mol. Mass.:
409.5164
SMILES:
CC1(C)COC(=O)CCCCCCCCCOC(=O)C2CCCCN2C(=O)C1=O
Structure:
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