Reaction Details Report a problem with these data
Target
Beta-1,4-galactosyltransferase 1
Ligand
BDBM50283877
Substrate
n/a
Meas. Tech.
ChEMBL_37695 (CHEMBL648989)
Ki
850000±n/a nM
Citation
 Field, RA; Neville, DC; Smith, RW; Ferguson, MA Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase Bioorg Med Chem Lett 4:391-394 (1994)    Article 
Target
Name:
Beta-1,4-galactosyltransferase 1
Synonyms:
β-1,4-Galactosyltransferase I (β4GalT) | B4GALT1 | B4GT1_BOVIN | Beta-1,4-galactosyltransferase 1 | GALT | GGTB2
Type:
Enzyme
Mol. Mass.:
44860.74
Organism:
Bos taurus (Cattle)
Description:
P08037
Residue:
402
Sequence:
MKFREPLLGGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLRRLPQLVGVHPPLQGSSHGAAAIGQPSGELRLRGVAPPPPLQNSSKPRSRAPSNLDAYSHPGPGPGPGSNLTSAPVPSTTTRSLTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGRYTPMDCISPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGESMFNRAKLLNVGFKEALKDYDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLSINGFPNNYWGWGGEDDDIYNRLAFRGMSVSRPNAVIGKCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYMVLEVQRYPLYTKITVDIGTPS
  
Inhibitor
Name:
BDBM50283877
Synonyms:
CHEMBL125848 | N-((2R,3R,4S,5S,6S)-5-Amino-2-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-acetamide
Type:
Small organic molecule
Emp. Form.:
C15H22N2O5
Mol. Mass.:
310.3456
SMILES:
CC(=O)N[C@@H]1[C@@H](O)[C@H](N)[C@@H](CO)O[C@H]1OCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: