Reaction Details Report a problem with these data
Target
Type-1 angiotensin II receptor
Ligand
BDBM50284295
Substrate
n/a
Meas. Tech.
ChEMBL_36796 (CHEMBL650316)
IC50
298±n/a nM
Citation
 Hill, DT; Girard, GR; Weinstock, J; Edwards, RM; Weidley, EF; Ohlstein, E; Peishoff, CE; Baker, E; Aiyar, N D and L-N-[(1-benzyl-1H-imidazol-5-yl)-alkyl]-amino acids as angiotensin II AT-1 antagonists Bioorg Med Chem Lett 5:19-24 (1995)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:
Protein
Mol. Mass.:
41080.75
Organism:
Homo sapiens (Human)
Description:
P30556
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
  
Inhibitor
Name:
BDBM50284295
Synonyms:
4-{2-Butyl-5-[(carboxymethyl-amino)-methyl]-imidazol-1-ylmethyl}-benzoic acid | CHEMBL78345
Type:
Small organic molecule
Emp. Form.:
C18H23N3O4
Mol. Mass.:
345.3929
SMILES:
CCCCc1ncc(CNCC(O)=O)n1Cc1ccc(cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: