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TargetMatrix metalloproteinase-7 (MMP7)
LigandBDBM50284756
Substrate/Competitorn/a
Meas. Tech.ChEBML_105051
Ki 850±n/a nM
Citation Castelhano, ALBilledeau, RDewdney, NDonnelly, SHorne, SKurz, LJLiak, TJMartin, RUppington, RYuan, ZKrantz, A Novel indolactam-based inhibitors of matrix metalloproteinases Bioorg Med Chem Lett5:1415-1420 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-7 (MMP7)
Name:Matrix metalloproteinase 7
Synonyms:Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7)
Type:Enzyme
Mol. Mass.:29681.54
Organism:Homo sapiens (Human)
Description:P09237
Residue:267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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  Blast E-value cutoff:
BDBM50284756
NameBDBM50284756
Synonyms:(R)-5-Methyl-3-((S)-9-oxo-1,8-diaza-tricyclo[10.6.1.0*13,18*]nonadeca-12(19),13(18),14,16-tetraen-10-ylcarbamoyl)-hexanoic acid | 5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID | CHEMBL282146
TypeSmall organic molecule
Emp. Form.C25H35N3O4
Mol. Mass.441.5631
SMILESCC(C)C[C@H](CC(O)=O)C(=O)N[C@H]1Cc2cn(CCCCCCNC1=O)c1ccccc21
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a