BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMatrix metalloproteinase-7 (MMP7)
LigandBDBM50284754
Substrate/Competitorn/a
Meas. Tech.ChEBML_105051
Ki 114±n/a nM
Citation Castelhano, ALBilledeau, RDewdney, NDonnelly, SHorne, SKurz, LJLiak, TJMartin, RUppington, RYuan, ZKrantz, A Novel indolactam-based inhibitors of matrix metalloproteinases Bioorg Med Chem Lett5:1415-1420 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-7 (MMP7)
Name:Matrix metalloproteinase 7
Synonyms:Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7)
Type:Enzyme
Mol. Mass.:29681.54
Organism:Homo sapiens (Human)
Description:P09237
Residue:267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50284754
NameBDBM50284754
Synonyms:(S)-2-Mercaptomethyl-4-methyl-pentanoic acid ((S)-9-oxo-1,8-diaza-tricyclo[10.6.1.0*13,18*]nonadeca-12(19),13(18),14,16-tetraen-10-yl)-amide | CHEMBL285112
TypeSmall organic molecule
Emp. Form.C24H35N3O2S
Mol. Mass.429.619
SMILESCC(C)C[C@H](CS)C(=O)N[C@H]1Cc2cn(CCCCCCNC1=O)c1ccccc21
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a