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Target
Mu-type opioid receptor
Ligand
BDBM50421363
Substrate
n/a
Meas. Tech.
ChEMBL_146693 (CHEMBL753770)
Kd
0.400000±n/a nM
Citation
 Bidlack, JM; Kaplan, RA; Sebastian, A; Seyed-Mozaffari, A; Hutchinson, I; Archer, S N-Methyl and N-cyclopropylmethyl-14α,14′β-[dithiobis[(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydro-5β-methyl-morphinone) MET-TAMO and N-CPM-MET-TAMO: Synthesis and opioid binding properties Bioorg Med Chem Lett 5:1695-1700 (1995)    Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45038.37
Organism:
CALF
Description:
OPIATE Mu 2 0 CALF::P79350
Residue:
401
Sequence:
MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
  
Inhibitor
Name:
BDBM50421363
Synonyms:
CHEMBL2304424
Type:
Small organic molecule
Emp. Form.:
C46H54N4O8S2
Mol. Mass.:
855.073
SMILES:
C[C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)CSSCC(=O)N[C@]12CCC(=O)[C@]4(C)Oc5c6c(C[C@H]1N(CC1CC1)CC[C@@]246)ccc5O)ccc3O
Structure:
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