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Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50285110
Substrate
n/a
Meas. Tech.
ChEMBL_154799 (CHEMBL761678)
IC50
1300000±n/a nM
Citation
 Boschetti, CE; Mata, EG; Mascaretti, OA; Cricco, JA; Coux, G; Roveri, OA Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones Bioorg Med Chem Lett 5:2033-2036 (1995)    Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50285110
Synonyms:
(2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid tert-butyl ester | CHEMBL304889
Type:
Small organic molecule
Emp. Form.:
C12H18ClNO5S
Mol. Mass.:
323.793
SMILES:
CC(C)(C)OC(=O)[C@@H]1N2[C@@H]([C@@H](Cl)C2=O)S(=O)(=O)C1(C)C
Structure:
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