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Target
Beta-lactamase 1
Ligand
BDBM50285123
Substrate
n/a
Meas. Tech.
ChEBML_40228
IC50
>5000000±n/a nM
Citation
 Danelon, GO; Mata, EG; Mascaretti, OA; Girardini, J; Marro, M; Roveri, OA Synthesis and β-lactamase inhibitory evaluation of novel 6α-halo-2β-chloromethyl-2α-methylpenam-3α-carboxylic acids and their sulfones and 6α-halo-2β-mercaptobenzothiazolylmethyl-2α-methylpenam-3α-carboxylic acids Bioorg Med Chem Lett 5:2037-2040 (1995)    Article 
Target
Name:
Beta-lactamase 1
Synonyms:
BLAC_BACCE | blaY
Type:
PROTEIN
Mol. Mass.:
33326.66
Organism:
Bacillus cereus
Description:
ChEMBL_40230
Residue:
306
Sequence:
MILKNKRMLKIGICVGILGLSITSLEAFTGESLQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTISYRPNERFAFASTYKALAAGVLLQQNSIDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRKILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNSAPIIVLISSKDEKEAIYNDQLIAEATKVIVKGS
  
Inhibitor
Name:
BDBM50285123
Synonyms:
(2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-6-bromo-3-methyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL293384
Type:
Small organic molecule
Emp. Form.:
C15H13BrN2O3S3
Mol. Mass.:
445.374
SMILES:
C[C@@]1(CSc2nc3ccccc3s2)S[C@@H]2[C@@H](Br)C(=O)N2[C@H]1C(O)=O
Structure:
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