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Target5-hydroxytryptamine receptor 1D
LigandBDBM50285319
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1626
IC50 1.98±n/a nM
Citation LeBoulluec, KLMattson, RJMahle, CDMcGovern, RTNowak, HPGentile, AJ Bivalent indoles exhibiting serotonergic binding affinity Bioorg Med Chem Lett5:123-126 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:Serotonin (5-HT) receptor
Synonyms:5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | Serotonin Receptor 1D
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41920.63
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50285319
NameBDBM50285319
Synonyms:3-(4-Heptylamino-cyclohex-1-enyl)-1H-indole-5-carboxylic acid amide | CHEMBL417650
TypeSmall organic molecule
Emp. Form.C22H31N3O
Mol. Mass.353.501
SMILESCCCCCCCNC1CCC(=CC1)c1c[nH]c2ccc(cc12)C(N)=O |c:11|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a