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Target
Dopamine beta-hydroxylase
Ligand
BDBM50286813
Substrate
n/a
Meas. Tech.
ChEBML_59304
Ki
400000±n/a nM
Citation
 Eydoux, F; Chlenov, MA; Réglier, M Synthesis of indane derivatives as mechanism-based inhibitors of dopamine β-hydroxylase Bioorg Med Chem Lett 5:941-944 (1995)    Article 
Target
Name:
Dopamine beta-hydroxylase
Synonyms:
DBH | DOPO_BOVIN
Type:
PROTEIN
Mol. Mass.:
68136.39
Organism:
Bos taurus
Description:
ChEMBL_50738
Residue:
610
Sequence:
MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISYAQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDSQQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSGLHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIVMYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMELGLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARDGRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSFNREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGPTVLNISGGKG
  
Inhibitor
Name:
BDBM50286813
Synonyms:
3-Methoxy-1,1a,6,6a-tetrahydro-1-aza-cyclopropa[a]indene | CHEMBL170486
Type:
Small organic molecule
Emp. Form.:
C10H11NO
Mol. Mass.:
161.2004
SMILES:
COc1ccc2CC3NC3c2c1
Structure:
Search PDB for entries with ligand similarity: