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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50288809
Substrate
n/a
Meas. Tech.
ChEMBL_159618 (CHEMBL760099)
IC50
190±n/a nM
Citation
 Freskos, JN; Bertenshaw, DE; Getman, DP; Heintz, RM; Mischke, BV; Blystone, LW; Bryant, ML; Funckes-Shippy, C; Houseman, KA; Kishore, NN; Kocan, GP; Mehta, PP (Hydroxyethyl) sulfonamide HIV-1 Protease inhibitors: Identification of the 2-methylbenzoyl moiety at P-2 Bioorg Med Chem Lett 6:445-450 (1996)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50288809
Synonyms:
CHEMBL141398 | N-{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-propyl}-2-methoxy-benzamide
Type:
Small organic molecule
Emp. Form.:
C29H36N2O6S
Mol. Mass.:
540.671
SMILES:
COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1OC
Structure:
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