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Target
Endothelin receptor type B
Ligand
BDBM50289656
Substrate
n/a
Meas. Tech.
ChEBML_63513
IC50
>1000±n/a nM
Citation
 Suzawa, T; Shibata, K; Tanaka, T; Matsuda, Y; Yamasaki, M RES-701-1/endothelin-1 hybrid peptide having a potent binding activity for type B receptor Bioorg Med Chem Lett 7:1715-1720 (1997)    Article 
Target
Name:
Endothelin receptor type B
Synonyms:
EDNRB | EDNRB_BOVIN | Endothelin receptor ET-B
Type:
PROTEIN
Mol. Mass.:
49389.50
Organism:
Bos taurus
Description:
ChEMBL_63513
Residue:
441
Sequence:
MQPLPSLCGRALVALILACGVAGIQAEEREFPPAGATQPLPGTGEMMETPTETSWPGRSNASDPRSSATPQIPRGGRMAGIPPRTPPPCDGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAKDWPFGVEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAVGFDIITSDHIGNKLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITALFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQHDPRRCEFLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
  
Inhibitor
Name:
BDBM50289656
Synonyms:
CHEMBL416287 | RES-701-1
Type:
Small organic molecule
Emp. Form.:
C41H53N13O13
Mol. Mass.:
935.9388
SMILES:
C[C@@H](O)[C@H]1NC(=O)CNC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC(N)=O)NC(=O)CNC(=O)C[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC1=O)C(O)=O
Structure:
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