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Target
Progesterone receptor
Ligand
BDBM50290370
Substrate
n/a
Meas. Tech.
ChEBML_159701
IC50
1381±n/a nM
Citation
 Connolly, PJ; Wetter, SK; Beers, KN; Hamel, SC; Haynes-Johnson, D; Kiddoe, M; Kraft, P; Lai, MT; Campen, C; Palmer, S; Phillips, A Synthesis and progesterone receptor binding affinity of substituted 1-phenyl-7-benzyl-4,5,6,7-tetrahydro-1H-indazoles Bioorg Med Chem Lett 7:2551-2556 (1997)    Article 
Target
Name:
Progesterone receptor
Synonyms:
NR3C3 | PGR | PRGR_RABIT
Type:
PROTEIN
Mol. Mass.:
98665.51
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_775980
Residue:
930
Sequence:
MTELKAKEPRAPHVAGGAPSPTEVGSQLLGRPDPGPFQGSQTSEASSVVSAIPISLDGLLFPRPCQGQNPPDGKTQDPPSLSDVEGAFPGVEAPEGAGDSSSRPPEKDSGLLDSVLDTLLAPSGPGQSHASPATCEAISPWCLFGPDLPEDPRAAPATKGVLAPLMSRPEDKAGDSSGTAAAHKVLPRGLSPSRQLLLPSSGSPHWPAVKPSPQPAAVQVDEEDSSESEGTVGPLLKGQPRALGGTAAGGGAAPVASGAAAGGVALVPKEDSRFSAPRVSLAEQDAPVAPGRSPLATSVVDFIHVPILPLNHAFLATRTRQLLEGESYDGGAAAASPFVPQRGSPSASSTPVAGGDFPDCTYPPDAEPKDDAFPLYGDFQPPALKIKEEEEAAEAAARSPRTYLVAGANPAAFPDFQLAAPPPPSLPPRVPSSRPGEAAVAASPGSASVSSSSSSGSTLECILYKAEGAPPQQGPFAPLPCKPPGAGACLLPRDGLPSTSASGAAAGAAPALYPTLGLNGLPQLGYQAAVLKEGLPQVYTPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNESQRITFSPSQEIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQSQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
  
Inhibitor
Name:
BDBM50290370
Synonyms:
Benzyl-[1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-ylmethyl]-amine | CHEMBL314419
Type:
Small organic molecule
Emp. Form.:
C32H30FN3
Mol. Mass.:
475.5991
SMILES:
Fc1ccc(cc1)-n1nc(CNCc2ccccc2)c2CCCC(Cc3cccc4ccccc34)c12
Structure:
Search PDB for entries with ligand similarity: