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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50291350
Substrate
n/a
Meas. Tech.
ChEBML_1552
Ki
13±n/a nM
Citation
 Baxter, EW; Reitz, AB Hindered rotation congeners of mazapertine: High affinity ligands for the 5-HT1A receptor Bioorg Med Chem Lett 7:763-768 (1997)    Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50291350
Synonyms:
CHEMBL423632 | Piperidin-1-yl-[3-(1,3,4,9-tetrahydro-beta-carbolin-2-ylmethyl)-phenyl]-methanone
Type:
Small organic molecule
Emp. Form.:
C24H27N3O
Mol. Mass.:
373.4907
SMILES:
O=C(N1CCCCC1)c1cccc(CN2CCc3c(C2)[nH]c2ccccc32)c1
Structure:
Search PDB for entries with ligand similarity: