Target
Matrix metalloproteinase-9
Ligand
BDBM50291445
Substrate
n/a
Meas. Tech.
ChEMBL_105665 (CHEMBL718978)
IC50
30±n/a nM
Citation
 Baxter, ADBird, JBhogal, RMassil, TMinton, KJMontana, JOwen, DA A novel series of matrix metalloproteinase inhibitors for the treatment of inflammatory disorders Bioorg Med Chem Lett 7:897-902 (1997)    Article 
Target
Name:
Matrix metalloproteinase-9
Synonyms:
MMP9_RAT | Matrix metalloproteinase 9 | Matrix metalloproteinase-9 (MMP-9) | Mmp9
Type:
n/a
Mol. Mass.:
78603.01
Organism:
Rattus norvegicus (Rat)
Description:
P50282
Residue:
708
Sequence:
MSPWQPLLLVLLALGYSFAAPHQRQPTYVVFPRDLKTSNLTDTQLAEDYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSETLKAIRSPRCGVPDVGKFQTFDGDLKWHHHNITYWIQSYTEDLPRDVIDDSFARAFAVWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDRKYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKADGFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTSEGRSDGRLWCATTSNFDADKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIHHLYGRGSKPDPRPPATTAAEPQPTAPPTMCSTAPPMAYPTGGPTVAPTGAPSPGPTGPPTAGPSEAPTESSTPDDNPCNVDVFDAIADIQGALHFFKDGRYWKFSNHGGNQLQGPFLIARTWPAFPSKLNSAFEDPQPKKIFFFLWAQMWVYTGQSVLGPRSLDKLGLGSEVTLVTGLLPRRGGKALLISRERIWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFQYQDKAYFCHDKYFWRVSFHNRVNQVDHVAYVTYDLLQCP
  
Inhibitor
Name:
BDBM50291445
Synonyms:
(S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic acid [(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-amide | CHEMBL426028
Type:
Small organic molecule
Emp. Form.:
C20H28N4O3S
Mol. Mass.:
404.526
SMILES:
CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)CS
Structure:
Search PDB for entries with ligand similarity: