Reaction Details Report a problem with these data
Target
Orexin receptor type 2
Ligand
BDBM50412862
Substrate
n/a
Meas. Tech.
ChEMBL_495784 (CHEMBL1007903)
Ki
2511.89±n/a nM
Citation
 Boss, C; Brisbare-Roch, C; Jenck, F Biomedical application of orexin/hypocretin receptor ligands in neuroscience. J Med Chem 52:891-903 (2009) [PubMed]  Article 
Target
Name:
Orexin receptor type 2
Synonyms:
HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R
Type:
Protein
Mol. Mass.:
50710.53
Organism:
Homo sapiens (Human)
Description:
O43614
Residue:
444
Sequence:
MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW
  
Inhibitor
Name:
BDBM50412862
Synonyms:
CHEMBL185136
Type:
Small organic molecule
Emp. Form.:
C19H20Cl2N2O3
Mol. Mass.:
395.28
SMILES:
CC1(C)OC[C@H](NC(=O)Nc2ccc(Cl)cc2Cl)[C@@H](O1)c1ccccc1 |r|
Structure:
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