Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50294670
Substrate
n/a
Meas. Tech.
ChEMBL_575807 (CHEMBL1024508)
Ki
37.5±n/a nM
Citation
 Pal, S; Choi, WJ; Choe, SA; Heller, CL; Gao, ZG; Chinn, M; Jacobson, KA; Hou, X; Lee, SK; Kim, HO; Jeong, LS Structure-activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists. Bioorg Med Chem 17:3733-8 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50294670
Synonyms:
(2R,3R,4R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-yl)-furan-3,4-diol | CHEMBL554275
Type:
Small organic molecule
Emp. Form.:
C10H12ClN5O3
Mol. Mass.:
285.687
SMILES:
CNc1nc(Cl)nc2n(cnc12)[C@@H]1OC[C@@H](O)[C@H]1O |r|
Structure:
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