Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50298023
Substrate
n/a
Meas. Tech.
ChEMBL_585089 (CHEMBL1054355)
IC50
500±n/a nM
Citation
Balachandran, S; Rodge, A; Gadekar, PK; Yadav, VN; Kamath, D; Chetrapal-Kunwar, A; Bhatt, P; Srinivasan, S; Sharma, S; Vishwakarma, RA; Dagia, NM Novel derivatives of ISO-1 as potent inhibitors of MIF biological function. Bioorg Med Chem Lett 19:4773-6 (2009) [PubMed] Article
More Info.:
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA