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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50298299
Substrate
n/a
Meas. Tech.
ChEMBL_588489 (CHEMBL1040387)
IC50
>10000±n/a nM
Citation
 Ahmed, A; Choo, H; Cho, YS; Park, WK; Pae, AN Identification of novel serotonin 2C receptor ligands by sequential virtual screening. Bioorg Med Chem 17:4559-68 (2009) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
51836.79
Organism:
Homo sapiens (Human)
Description:
P28335
Residue:
458
Sequence:
MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
  
Inhibitor
Name:
BDBM50298299
Synonyms:
CHEMBL574303 | N-(2-(4-methylpiperazin-1-yl)ethyl)-1H-pyrrolo[3,2-h]quinoline-2-carboxamide
Type:
Small organic molecule
Emp. Form.:
C19H23N5O
Mol. Mass.:
337.4188
SMILES:
CN1CCN(CCNC(=O)c2cc3ccc4cccnc4c3[nH]2)CC1
Structure:
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