Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50299303
Substrate
n/a
Meas. Tech.
ChEMBL_590237 (CHEMBL1059274)
Ki
24±n/a nM
Citation
 Nasr, G; Petit, E; Supuran, CT; Winum, JY; Barboiu, M Carbonic anhydrase II-induced selection of inhibitors from a dynamic combinatorial library of Schiff's bases. Bioorg Med Chem Lett 19:6014-7 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50299303
Synonyms:
4-((4-tert-butylbenzylideneamino)methyl)benzenesulfonamide | CHEMBL568478
Type:
Small organic molecule
Emp. Form.:
C18H22N2O2S
Mol. Mass.:
330.444
SMILES:
CC(C)(C)c1ccc(\C=N\Cc2ccc(cc2)S(N)(=O)=O)cc1
Structure:
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