Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50303027
Substrate
n/a
Meas. Tech.
ChEMBL_596965 (CHEMBL1038202)
IC50
427±n/a nM
Citation
 Lee, SH; Seo, HJ; Kim, MJ; Kang, SY; Lee, SH; Ahn, K; Lee, M; Han, HK; Kim, J; Lee, J Pentacycle derivatives as cannabinoid CB1 receptor ligands. Bioorg Med Chem Lett 19:6632-6 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50303027
Synonyms:
2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole | CHEMBL585526
Type:
Small organic molecule
Emp. Form.:
C24H19BrCl2N6S2
Mol. Mass.:
606.388
SMILES:
Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: