Reaction Details Report a problem with these data
Target
S-ribosylhomocysteine lyase
Ligand
BDBM50304169
Substrate
n/a
Meas. Tech.
ChEMBL_601071 (CHEMBL1071830)
Ki
7900±n/a nM
Citation
 Wnuk, SF; Robert, J; Sobczak, AJ; Meyers, BP; Malladi, VL; Zhu, J; Gopishetty, B; Pei, D Inhibition of S-ribosylhomocysteinase (LuxS) by substrate analogues modified at the ribosyl C-3 position. Bioorg Med Chem 17:6699-706 (2009) [PubMed]  Article 
Target
Name:
S-ribosylhomocysteine lyase
Synonyms:
LUXS_BACSU | luxS | ytjB
Type:
PROTEIN
Mol. Mass.:
17709.00
Organism:
Bacillus subtilis
Description:
ChEMBL_764478
Residue:
157
Sequence:
MPSVESFELDHNAVVAPYVRHCGVHKVGTDGVVNKFDIRFCQPNKQAMKPDTIHTLEHLLAFTIRSHAEKYDHFDIIDISPMGCQTGYYLVVSGEPTSAEIVDLLEDTMKEAVEITEIPAANEKQCGQAKLHDLEGAKRLMRFWLSQDKEELLKVFG
  
Inhibitor
Name:
BDBM50304169
Synonyms:
(2S)-2-amino-4-(((2R,3S,4S)-3-bromo-4,5-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid | CHEMBL594964
Type:
Small organic molecule
Emp. Form.:
C9H16BrNO5S
Mol. Mass.:
330.196
SMILES:
N[C@@H](CCSC[C@H]1OC(O)[C@H](O)[C@@H]1Br)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: