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Target
Beta-2 adrenergic receptor
Ligand
BDBM50087513
Substrate
n/a
Meas. Tech.
ChEMBL_603940 (CHEMBL1043293)
Ki
15800±n/a nM
Citation
 Pooput, C; Rosemond, E; Karpiak, J; Deflorian, F; Vilar, S; Costanzi, S; Wess, J; Kirk, KL Structural basis of the selectivity of the beta(2)-adrenergic receptor for fluorinated catecholamines. Bioorg Med Chem 17:7987-92 (2009) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50087513
Synonyms:
(R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol | 2-fluoronorepinehprine | CHEMBL40317
Type:
Small organic molecule
Emp. Form.:
C8H10FNO3
Mol. Mass.:
187.1683
SMILES:
NC[C@H](O)c1cc(O)c(O)cc1F
Structure:
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