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Target
Cannabinoid receptor 2
Ligand
BDBM50304924
Substrate
n/a
Meas. Tech.
ChEMBL_606629 (CHEMBL1071856)
EC50
22±n/a nM
Citation
 Sellitto, I; Le Bourdonnec, B; Worm, K; Goodman, A; Savolainen, MA; Chu, GH; Ajello, CW; Saeui, CT; Leister, LK; Cassel, JA; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability. Bioorg Med Chem Lett 20:387-91 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50304924
Synonyms:
CHEMBL602591 | N-(3-(azepan-1-ylsulfonyl)-4,5-dimethylphenyl)-2,2-dimethylbutanamide
Type:
Small organic molecule
Emp. Form.:
C20H32N2O3S
Mol. Mass.:
380.545
SMILES:
CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCCC1
Structure:
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