Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50292722
Substrate
n/a
Meas. Tech.
ChEMBL_620094 (CHEMBL1109349)
pH
6±n/a
Ki
78500±n/a nM
Comments
extracted
Citation
 Dossi, K; Tsirkone, VG; Hayes, JM; Matousek, J; Poucková, P; Soucek, J; Zadinova, M; Zographos, SE; Leonidas, DD Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors. Eur J Med Chem 44:4496-508 (2009) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50292722
Synonyms:
3'-UMP | 3'-uridylic acid | CHEMBL460741
Type:
Small organic molecule
Emp. Form.:
C9H13N2O9P
Mol. Mass.:
324.1813
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1ccc(=O)[nH]c1=O |r|
Structure:
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