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TargetMatrix metalloproteinase-2 (MMP-2)
LigandBDBM50250808
Substrate/Competitorn/a
Meas. Tech.ChEMBL_622215
IC50 10200±n/a nM
Citation Murata, TSasaki, KSato, KYoshizaki, FYamada, HMutoh, HUmehara, KMiyase, TWarashina, TAoshima, HTabata, HMatsubara, K Matrix metalloproteinase-2 inhibitors from Clinopodium chinense var. parviflorum. J Nat Prod72:1379-84 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-2 (MMP-2)
Name:Matrix metalloproteinase-2 (MMP-2)
Synonyms:72 kDa type IV collagenase
Type:n/a
Mol. Mass.:74137.51
Organism:Rattus norvegicus (Rat)
Description:P33436
Residue:662
Sequence:
MEARLVWGVLVGPLRVLCVLCCLLGHAIAAPSPIIKFPGDVSPKTDKELAVQYLNTFYGC
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
KNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
GREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNGDGQPCKFPFRFQGT
SYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
MAPIYTYTKNFRLSNDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGI
AQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
EYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFSGDKFWRYNEVKKKM
DPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL
GC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50250808
n/a
NameBDBM50250808
Synonyms:CHEMBL518243 | lithospermic acid
TypeSmall organic molecule
Emp. Form.C27H22O12
Mol. Mass.538.4564
SMILESOC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c1ccc(O)c2O[C@@H]([C@@H](C(O)=O)c12)c1ccc(O)c(O)c1 |r|
Structure
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