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TargetHistamine H3 receptor
LigandBDBM50311776
Substrate/Competitorn/a
Meas. Tech.ChEMBL_619277
Ki 23±n/a nM
Citation Łazewska, DWiecek, MLigneau, XKottke, TWeizel, LSeifert, RSchunack, WStark, HKiec-Kononowicz, K Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates. Bioorg Med Chem Lett19:6682-5 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Histamine H3 receptor
Name:Histamine H3 receptor
Synonyms:HH3R
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:48607.98
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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  Blast E-value cutoff:
BDBM50311776
NameBDBM50311776
Synonyms:(R)-3-(1H-imidazol-4-yl)propyl heptan-2-ylcarbamate | CHEMBL1079918
TypeSmall organic molecule
Emp. Form.C14H25N3O2
Mol. Mass.267.3672
SMILESCCCCC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 |r|
Structure
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n/a