Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50211685
Substrate
n/a
Meas. Tech.
ChEMBL_616080 (CHEMBL1102043)
Ki
2821±n/a nM
Citation
 Eastwood, P; Gonzalez, J; Paredes, S; Nueda, A; Domenech, T; Alberti, J; Vidal, B Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists. Bioorg Med Chem Lett 20:1697-700 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50211685
Synonyms:
4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine | 4'-(furan-2-yl)-N-(pyridin-3-yl)-4,5'-bipyrimidin-2'-amine | CHEMBL375293
Type:
Small organic molecule
Emp. Form.:
C17H12N6O
Mol. Mass.:
316.3168
SMILES:
N(c1cccnc1)c1ncc(-c2ccncn2)c(n1)-c1ccco1
Structure:
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