Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50312949
Substrate
n/a
Meas. Tech.
ChEMBL_616081 (CHEMBL1102044)
Ki
1866±n/a nM
Citation
 Eastwood, P; Gonzalez, J; Paredes, S; Nueda, A; Domenech, T; Alberti, J; Vidal, B Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists. Bioorg Med Chem Lett 20:1697-700 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50312949
Synonyms:
CHEMBL1079803 | N-(3'-chloro-2-(furan-2-yl)-3,4'-bipyridin-6-yl)cyclopropanecarboxamide
Type:
Small organic molecule
Emp. Form.:
C18H14ClN3O2
Mol. Mass.:
339.776
SMILES:
Clc1cnccc1-c1ccc(NC(=O)C2CC2)nc1-c1ccco1
Structure:
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