Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetLmbE-related protein
LigandBDBM50315606
Substrate/Competitorn/a
Meas. Tech.ChEMBL_627600
Ki 94000±n/a nM
Citation Gammon, DWSteenkamp, DJMavumengwana, VMarakalala, MJMudzunga, TTHunter, RMunyololo, M Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol. Bioorg Med Chem18:2501-14 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
LmbE-related protein
Name:LmbE-related protein
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:31733.34
Organism:Mycobacterium tuberculosis
Description:ChEMBL_627600
Residue:303
Sequence:
MSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEVIGDRWAQLTADH
ADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGMAGTDQRSQRRFVDADPRQTVGA
LVAIIRELRPHVVVTYDPNGGYGHPDHVHTHTVTTAAVAAAGVGSGTADHPGDPWTVPKF
YWTVLGLSALISGARALVPDDLRPEWVLPRADEIAFGYSDDGIDAVVEADEQARAAKVAA
LAAHATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLLAGLGFTA
SGT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50315606
NameBDBM50315606
Synonyms:CHEMBL1093142 | Phenyl-2-deoxy-2-[3'-(8''-hydroxy-3''-methyl-1'',4''-dioxo-1'',4''-dihydronaphthalen-2''-yl)pentanamido]-1-thio-alpha-D-glucopyranoside
TypeSmall organic molecule
Emp. Form.C28H31NO8S
Mol. Mass.541.613
SMILESCc1c(O)c2cccc(O)c2c(O)c1C=CCCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1Sc1ccccc1 |r,w:15.17|
Structure
n/a