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Target
Hyaluronidase-1
Ligand
BDBM50316416
Substrate
n/a
Meas. Tech.
ChEMBL_628271 (CHEMBL1111859)
IC50
173000±n/a nM
Citation
 Iwanaga, A; Kusano, G; Warashina, T; Miyase, T Phenolic constituents of the aerial parts of Cimicifuga simplex and Cimicifuga japonica. J Nat Prod 73:609-12 (2010) [PubMed]  Article 
Target
Name:
Hyaluronidase-1
Synonyms:
HYAL1 | HYAL1_HUMAN | Hyaluronidase | Hyaluronidase-1 | Hyaluronoglucosaminidase-1 | LUCA1
Type:
Protein
Mol. Mass.:
48369.09
Organism:
Homo sapiens (Human)
Description:
Q1279
Residue:
435
Sequence:
MAAHLLPICALFLTLLDMAQGFRGPLLPNRPFTTVWNANTQWCLERHGVDVDVSVFDVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPDWPAPQVEAVAQDQFQGAARAWMAGTLQLGRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQNDQLGWLWGQSRALYPSIYMPAVLEGTGKSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQIFYDTTNHFLPLDELEHSLGESAAQGAAGVVLWVSWENTRTKESCQAIKEYMDTTLGPFILNVTSGALLCSQALCSGHGRCVRRTSHPKALLLLNPASFSIQLTPGGGPLSLRGALSLEDQAQMAVEFKCRCYPGWQAPWCERKSMW
  
Inhibitor
Name:
BDBM50316416
Synonyms:
CHEMBL1096937 | Cimicifugic acid M
Type:
Small organic molecule
Emp. Form.:
C20H18O9
Mol. Mass.:
402.3515
SMILES:
OC(=O)[C@@H](OC(=O)\C=C\c1ccc(O)c(O)c1)[C@](O)(Cc1ccccc1)C(O)=O |r|
Structure:
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