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Target
Virokine/NFkB inhibitor
Ligand
BDBM50316626
Substrate
n/a
Meas. Tech.
ChEMBL_632000 (CHEMBL1108211)
IC50
3600±n/a nM
Citation
 Cheltsov, AV; Aoyagi, M; Aleshin, A; Yu, EC; Gilliland, T; Zhai, D; Bobkov, AA; Reed, JC; Liddington, RC; Abagyan, R Vaccinia virus virulence factor N1L is a novel promising target for antiviral therapeutic intervention. J Med Chem 53:3899-906 (2010) [PubMed]  Article 
Target
Name:
Virokine/NFkB inhibitor
Synonyms:
N1L
Type:
PROTEIN
Mol. Mass.:
13954.85
Organism:
Vaccinia virus
Description:
ChEMBL_631987
Residue:
117
Sequence:
MRTLLIRYILWRNDNDQTYYNDDFKKLMLLDELVDDGDVCTLIKNMRMTLSDGPLLDRLNQPVNNIEDAKRMIAISAKVARDIGERSEIRWEESFTILFRMIETYFDDLMIDLYGEK
  
Inhibitor
Name:
BDBM50316626
Synonyms:
2'-methoxy-1,1'-binaphthyl-2-ol | CHEMBL1094828
Type:
Small organic molecule
Emp. Form.:
C21H16O2
Mol. Mass.:
300.3505
SMILES:
COc1ccc2ccccc2c1-c1c(O)ccc2ccccc12 |(12.2,-23.98,;10.87,-23.22,;9.53,-23.99,;9.54,-25.53,;8.21,-26.31,;6.87,-25.54,;5.54,-26.32,;4.21,-25.56,;4.2,-24.01,;5.53,-23.24,;6.87,-24,;8.2,-23.23,;8.2,-21.7,;9.54,-20.92,;10.87,-21.69,;9.53,-19.37,;8.19,-18.61,;6.86,-19.38,;5.52,-18.62,;4.19,-19.39,;4.19,-20.94,;5.53,-21.71,;6.86,-20.93,)|
Structure:
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