Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50275147
Substrate
n/a
Meas. Tech.
ChEMBL_631800 (CHEMBL1108193)
Ki
>100000±n/a nM
Citation
 Nievergelt, AHuonker, PSchoop, RAltmann, KHGertsch, J Identification of serotonin 5-HT1A receptor partial agonists in ginger. Bioorg Med Chem 18:3345-51 (2010) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50275147
Synonyms:
6-Gingerol | BDBM50317427 | CHEMBL446043 | Gingerol | [6]-gingerol
Type:
Small organic molecule
Emp. Form.:
C17H26O4
Mol. Mass.:
294.3859
SMILES:
CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1 |r|
Structure:
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