Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetUracil nucleotide/cysteinyl leukotriene receptor
LigandBDBM50306710
Substrate/Competitorn/a
Meas. Tech.ChEMBL_631133
EC50 945±n/a nM
Citation Calleri, ECeruti, SCristalli, GMartini, CTemporini, CParravicini, CVolpini, RDaniele, SCaccialanza, GLecca, DLambertucci, CTrincavelli, MLMarucci, GWainer, IWRanghino, GFantucci, PAbbracchio, MPMassolini, G Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor. J Med Chem53:3489-501 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Uracil nucleotide/cysteinyl leukotriene receptor
Name:Uracil nucleotide/cysteinyl leukotriene receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41013.71
Organism:Homo sapiens
Description:ChEMBL_1353471
Residue:367
Sequence:
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENM
LFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHF
SGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLAC
AFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCY
LLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQ
RILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESS
LSAKSEL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50306710
NameBDBM50306710
Synonyms:((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl trihydrogen diphosphate | CHEMBL1094759 | CHEMBL590494
TypeSmall organic molecule
Emp. Form.C9H13IN2O12P2
Mol. Mass.530.0577
SMILESO[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(I)c(=O)[nH]c1=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a