Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetUracil nucleotide/cysteinyl leukotriene receptor
LigandBDBM50318028
Substrate/Competitorn/a
Meas. Tech.ChEMBL_631134
IC50 582±n/a nM
Citation Calleri, ECeruti, SCristalli, GMartini, CTemporini, CParravicini, CVolpini, RDaniele, SCaccialanza, GLecca, DLambertucci, CTrincavelli, MLMarucci, GWainer, IWRanghino, GFantucci, PAbbracchio, MPMassolini, G Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor. J Med Chem53:3489-501 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Uracil nucleotide/cysteinyl leukotriene receptor
Name:Uracil nucleotide/cysteinyl leukotriene receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41013.71
Organism:Homo sapiens
Description:ChEMBL_1353471
Residue:367
Sequence:
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENM
LFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHF
SGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLAC
AFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCY
LLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQ
RILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESS
LSAKSEL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50318028
NameBDBM50318028
Synonyms:CHEMBL1094760 | diammonium (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-[(hydrogen phosphonatooxy)methyl]oxolan-3-yl hydrogen phosphate
TypeSmall organic molecule
Emp. Form.C10H14ClN5O9P2
Mol. Mass.445.647
SMILESNc1nc(Cl)nc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a