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Target
P2Y purinoceptor 6
Ligand
BDBM50319143
Substrate
n/a
Meas. Tech.
ChEMBL_635659 (CHEMBL1119551)
EC50
80±n/a nM
Citation
 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications. J Med Chem 53:4488-501 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50319143
Synonyms:
CHEMBL1083764 | CHEMBL1198849 | N4-Methoxycytidine 5'-Triphosphate triethylammonium Salt
Type:
Small organic molecule
Emp. Form.:
C10H18N3O15P3
Mol. Mass.:
513.1823
SMILES:
CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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