Target
Phospholipid transfer protein
Ligand
BDBM50325134
Substrate
n/a
Meas. Tech.
ChEMBL_651691 (CHEMBL1228381)
IC50
85000±n/a nM
Citation
 Ling, CZheng, ZJiang, XCZhong, WLi, S Synthesis of a series of novel 2,4,5-trisubstituted selenazole compounds as potential PLTP inhibitors. Bioorg Med Chem Lett 20:5123-5 (2010) [PubMed]  Article 
Target
Name:
Phospholipid transfer protein
Synonyms:
PLTP | PLTP_HUMAN
Type:
PROTEIN
Mol. Mass.:
54741.32
Organism:
Homo sapiens (Human)
Description:
ChEMBL_651691
Residue:
493
Sequence:
MALFGALFLALLAGAHAEFPGCKIRVTSKALELVKQEGLRFLEQELETITIPDLRGKEGHFYYNISEVKVTELQLTSSELDFQPQQELMLQITNASLGLRFRRQLLYWFFYDGGYINASAEGVSIRTGLELSRDPAGRMKVSNVSCQASVSRMHAAFGGTFKKVYDFLSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDELVGIDYSLMKDPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESYFRAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVIDSPLKLELRVLAPPRCTIKPSGTTISVTASVTIALVPPDQPEVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYSNHSALESLALIPLQAPLKTMLQIGVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGADLHFAKGLREVIEKNRPADVRASTAPTPSTAAV
  
Inhibitor
Name:
BDBM50325134
Synonyms:
CHEMBL1222600 | N-(5-benzyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl)-4-nitrobenzamide
Type:
Small organic molecule
Emp. Form.:
C24H19N3O4Se
Mol. Mass.:
492.39
SMILES:
COc1ccc(cc1)-c1nc(NC(=O)c2ccc(cc2)[N+]([O-])=O)[se]c1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: