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Target
Phospholipid transfer protein
Ligand
BDBM50325137
Substrate
n/a
Meas. Tech.
ChEMBL_651691 (CHEMBL1228381)
IC50
25000±n/a nM
Citation
 Ling, C; Zheng, Z; Jiang, XC; Zhong, W; Li, S Synthesis of a series of novel 2,4,5-trisubstituted selenazole compounds as potential PLTP inhibitors. Bioorg Med Chem Lett 20:5123-5 (2010) [PubMed]  Article 
Target
Name:
Phospholipid transfer protein
Synonyms:
PLTP | PLTP_HUMAN
Type:
PROTEIN
Mol. Mass.:
54741.32
Organism:
Homo sapiens (Human)
Description:
ChEMBL_651691
Residue:
493
Sequence:
MALFGALFLALLAGAHAEFPGCKIRVTSKALELVKQEGLRFLEQELETITIPDLRGKEGHFYYNISEVKVTELQLTSSELDFQPQQELMLQITNASLGLRFRRQLLYWFFYDGGYINASAEGVSIRTGLELSRDPAGRMKVSNVSCQASVSRMHAAFGGTFKKVYDFLSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDELVGIDYSLMKDPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESYFRAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVIDSPLKLELRVLAPPRCTIKPSGTTISVTASVTIALVPPDQPEVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYSNHSALESLALIPLQAPLKTMLQIGVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGADLHFAKGLREVIEKNRPADVRASTAPTPSTAAV
  
Inhibitor
Name:
BDBM50325137
Synonyms:
CHEMBL1222733 | N-(4,5-diphenyl-1,3-selenazol-2-yl)-3,4,5-trihydroxybenzamide
Type:
Small organic molecule
Emp. Form.:
C22H16N2O4Se
Mol. Mass.:
451.33
SMILES:
Oc1cc(cc(O)c1O)C(=O)Nc1nc(c([se]1)-c1ccccc1)-c1ccccc1
Structure:
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