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Target
ELAV-like protein 1
Ligand
BDBM50326009
Substrate
n/a
Meas. Tech.
ChEMBL_654855 (CHEMBL1243899)
Kd
420±n/a nM
Citation
 Meisner, NC; Hintersteiner, M; Mueller, K; Bauer, R; Seifert, JM; Naegeli, HU; Ottl, J; Oberer, L; Guenat, C; Moss, S; Harrer, N; Woisetschlaeger, M; Buehler, C; Uhl, V; Auer, M Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat Chem Biol 3:508-15 (2007) [PubMed]  Article 
Target
Name:
ELAV-like protein 1
Synonyms:
ELAV1_HUMAN | ELAVL1 | HUR | Hu-antigen R
Type:
PROTEIN
Mol. Mass.:
36102.56
Organism:
Homo sapiens (Human)
Description:
ChEMBL_654855
Residue:
326
Sequence:
MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK
  
Inhibitor
Name:
BDBM50326009
Synonyms:
5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-one | CHEMBL1240928
Type:
Small organic molecule
Emp. Form.:
C13H10O4
Mol. Mass.:
230.2161
SMILES:
Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12
Structure:
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