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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM24776
Substrate
n/a
Meas. Tech.
ChEMBL_657596 (CHEMBL1247197)
IC50
990±n/a nM
Citation
 John, S; Thangapandian, S; Sakkiah, S; Lee, KW Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: pharmacophore modeling and molecular docking studies. Eur J Med Chem 45:4004-12 (2010) [PubMed]  Article 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Homo sapiens (Human)
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM24776
Synonyms:
1,4-Naphthoquinone | 1,4-Naphthoquinone (5a) | 1,4-dihydronaphthalene-1,4-dione | 1,4-naphtho-quinone, 3 | CHEMBL55934
Type:
Small organic molecule
Emp. Form.:
C10H6O2
Mol. Mass.:
158.1534
SMILES:
O=C1C=CC(=O)c2ccccc12 |c:2|
Structure:
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