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Target
Somatostatin receptor type 4
Ligand
BDBM50326874
Substrate
n/a
Meas. Tech.
ChEMBL_662925 (CHEMBL1252086)
IC50
180±n/a nM
Citation
 Abbenante, G; Becker, B; Blanc, S; Clark, C; Condie, G; Fraser, G; Grathwohl, M; Halliday, J; Henderson, S; Lam, A; Liu, L; Mann, M; Muldoon, C; Pearson, A; Premraj, R; Ramsdale, T; Rossetti, T; Schafer, K; Le Thanh, G; Tometzki, G; Vari, F; Verquin, G; Waanders, J; West, M; Wimmer, N; Yau, A; Zuegg, J; Meutermans, W Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold. J Med Chem 53:5576-86 (2010) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50326874
Synonyms:
CHEMBL1254882 | N-((2S,3R,4S,5S,6R)-6-(benzyloxymethyl)-5-hydroxy-2-(methylthio)-4-(naphthalen-2-ylmethoxy)tetrahydro-2H-pyran-3-yl)-3-(diaminomethyleneamino)propanamide
Type:
Small organic molecule
Emp. Form.:
C29H36N4O5S
Mol. Mass.:
552.685
SMILES:
[#6]-[#16]-[#6@@H]-1-[#8]-[#6@H](-[#6]-[#8]-[#6]-c2ccccc2)-[#6@@H](-[#8])-[#6@@H](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@H]-1-[#7]-[#6](=O)-[#6]-[#6]\[#7]=[#6](\[#7])-[#7] |r|
Structure:
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