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Target
D(3) dopamine receptor
Ligand
BDBM50328638
Substrate
n/a
Meas. Tech.
ChEMBL_665772 (CHEMBL1259263)
Ki
12000±n/a nM
Citation
 Bollinger, S; Hübner, H; Heinemann, FW; Meyer, K; Gmeiner, P Novel pyridylmethylamines as highly selective 5-HT(1A) superagonists. J Med Chem 53:7167-79 (2010) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50328638
Synonyms:
CHEMBL1258999 | benzofuran-3-yl(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C22H24FN3O2
Mol. Mass.:
381.4433
SMILES:
Cc1ccc(CNCC2(F)CCN(CC2)C(=O)c2coc3ccccc23)nc1
Structure:
Search PDB for entries with ligand similarity: