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Target
BiP isoform A
Ligand
BDBM50332791
Substrate
n/a
Meas. Tech.
ChEMBL_696628 (CHEMBL1641179)
IC50
58500±n/a nM
Citation
 Ispikoudi, M; Amvrazis, M; Kontogiorgis, C; Koumbis, AE; Litinas, KE; Hadjipavlou-Litina, D; Fylaktakidou, KC Convenient synthesis and biological profile of 5-amino-substituted 1,2,4-oxadiazole derivatives. Eur J Med Chem 45:5635-45 (2010) [PubMed]  Article 
Target
Name:
BiP isoform A
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
73317.49
Organism:
Glycine max
Description:
ChEMBL_696628
Residue:
664
Sequence:
MACSFSRGSSCFPLAIIVSLGCLFRDFSIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWSFTDSERLIGEAAKNLAAVNPERVIFDVKRLIGRKFEDKEVQRDMKLVPYKIVNKDGKPYIQEKIKDGETKVFSPEEISAMILTKMKETAEAFLGKKINDAVAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRIMEYFIKLINKKHKKDISKDSRALSKLRREAERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLQKNQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNADEAVAYGAAVQGSILSGEGGEETKDILLLDVAALTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQSTVSIQVFEGERSLTKDCRLLGKFELSGIPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNEKGRLSQEEIERMVREAEEFAEEDKKVKERIDARNSLETYVYNMKNQVSDKDKLADKLESDEKEKVETAVKEALEWLDDNQSVEKRYEEKLKEVEAVCNPIISAVYQRSGGAPGGGASGEDDDEDSHDEL
  
Inhibitor
Name:
BDBM50332791
Synonyms:
CHEMBL1630606 | N-Isopropyl-N-[3-(3-nitrophenyl)-1,2,4-oxadiazol-5-yl]acetamide
Type:
Small organic molecule
Emp. Form.:
C13H14N4O4
Mol. Mass.:
290.2747
SMILES:
CC(C)N(C(C)=O)c1nc(no1)-c1cccc(c1)[N+]([O-])=O
Structure:
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