Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM10859
Substrate
n/a
Meas. Tech.
ChEMBL_700659 (CHEMBL1645698)
Ki
516±n/a nM
Citation
 Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett 21:710-4 (2011) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
35119.71
Organism:
Stylophora pistillata
Description:
ChEMBL_700659
Residue:
316
Sequence:
MYFLWLISMIAAAMCQEYGYMSEQGVPTPSNWSKVFPLCGGKFQSPINIETKKVKKKSYPDLKISFDNPCGRVTGELLNAGHSPVVNIDSSKGGAKLSGGPLDCDEYALQQFHFHFGCENSRGSEHLIDSQAFPAQLHLVFFNKKYETFQNAVDKPDGLAVLGVLITATCPGNRVLGSFAKKLTKIIEEGASANVTAVDGIKLNYLMPYNNKQGDEDEDDEDIAGDDPDAVEEEEVDAKKKIKYYTYKGSLTTPPCYESVTWIVFKDKIKISNTQLKKFRKLKAQYGGAPGLMCDNIRPVQPLHKRKVYSVLSSRE
  
Inhibitor
Name:
BDBM10859
Synonyms:
4-methylbenzene-1-sulfonamide | CHEMBL574 | aromatic/heteroaromatic sulfonamide 4 | hCA inhibitor, 7
Type:
Small organic molecule
Emp. Form.:
C7H9NO2S
Mol. Mass.:
171.217
SMILES:
Cc1ccc(cc1)S(N)(=O)=O
Structure:
Search PDB for entries with ligand similarity: